INfluenza Vaccine to Effectively Stop Cardio Thoracic Events & Decompensated heart failure (INVESTED)

PI(s): Scott Solomon, Harvard Medical School; Orly Vardeny, University of Wisconsin - Madison

Project Summary: INVESTED assessed whether high-dose influenza vaccine compared with standard dose vaccine will reduce cardiopulmonary events in a high-risk cardiovascular population. The study found that the high-dose vaccine was not more effective to reduce death or cardiopulmonary hospitalizations among high cardiovascular risk patients.

Study Design: Multi-CRN Interventional Study

PaTH Partners:

  • Ohio State University (Garrie Haas, Site PI)
  • Temple University (Anuradha Paranjape, Site PI)
  • University of Pittsburgh (Kathleen McTigue, Site PI)

Sponsor: NIH

Coordinating Center: University of Wisconsin-Madison; Harvard Medical School; University of Toronto; Clinical Sciences Center, Madison, Wisconsin

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