Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE)
PI(s): Christopher Forrest
Project Summary: Hypertension worsens kidney function and can lead to end-stage kidney disease (ESKD), which in turn requires dialysis or transplantation. Thus, controlling blood pressure is a cornerstone of pediatric chronic kidney disease (CKD) treatment. PRESERVE is a 3-year study that will leverage the PCORnet® infrastructure to perform large-scale observational studies in support of a clinical trial arm of the study. More than 11,000 children are included in PRESERVE, which will provide critical information about blood pressure management in pediatric CDK.
Study Design: Multi-CRN Data only Observational
PaTH Partners:
Coordinating Center: Children's Hospital of Philadelphia